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De novo mutation

New mutation. A new mutation that was not previously present due to an error in the copying of genetic material or an error  in cell division. 

This may result in a family member being the first member in a family to have a genetic condition (dominant,  X-linked or chromosomal) as a result of a mutation in a gamete (egg or sperm) of one of the parents or in the fertilized egg itself.  A new mutation occurring in a somatic cell can result in cancer.

 

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Teaching Genetics