This series of factsheets, written by Professor Alain Li Wan Po, provides an insight into the impact of pharmacogenomics and associated sciences on current clinical practice, using real-life case-based examples.
Part 1: When usual doses lead to adverse effects: Dose level relationships
Part 2: When usual doses lead to adverse effects: Polymorphisms of metabolic enzymes
Part 3: The cancer treatment revolution: Controlling the renegade cell
Part 4: Gene therapy: repairing or replacing defective genes
Part 5: Genotyping the invader and developing new vaccines
Part 6: Pharmacogenetic Testing
Part 7: Genomics, stem cells and regenerative medicine
Part 8: Gene expression signatures
Complete series
This report describes the findings of a meeting held with pharmacy stakeholders in collaboration with the Royal Pharmaceutical Society of Great Britain.
A main recommendation was that the Centre should be involved in engaging pharmacy stakeholders to develop a genetics education framework for pharmacists in pre-registration education, continuing professional development and specialist training. The Centre is working with pharmacy groups to provide educators with support and clinically relevant teaching resources to be freely available from the Centre, such as the Reusable Learning Resources above.
In this article for "The Pharmacist" journal, Alain Li-Wan-Po and Peter Farndon introduce the science of pharmacogenetics and its implications for pharmacy practice, illustrated with examples from oncology and other areas.
"The technology for reliable pharmacogenetic testing is advancing fast, the need for optimising pharmacotherapy is ever present, and the Department of Health is keen to help the development of clinical services by the community pharmacist. Will pharmacists rise to the challenge of providing an appropriate pharmacogenetics advisory service?"
Last updated: 5 July 2011